PROBLEM TO BE SOLVED: To provide a novel pharmaceutical composition for intratumoral injection or direct injection to tumor lesion.SOLUTION: A pharmaceutical composition contains 2.0 M to 5.5 M of an effective therapeutic amount of Na+ (inorganic sodium salt and organic sodium salt) and 250 mM to 3.0 M of an effective therapeutic amount of Ca2+ (inorganic calcium salt and organic calcium salt) in aqueous solution, and provides synergistic and complementary double-wave cancer killing effect. A pharmaceutical preparation for intratumoral injection of malignant tumor, cancer, benign tumor, and non-malignant hyperplasia disease contains 5.0479 M of Na, 250 mM of Ca, an appropriate amount of distilled water, 10 ml of Ultravist 370, 20 mg of adrenalin at room temperature.SELECTED DRAWING: None【課題】腫瘍病変に腫瘍内注射または直接注射ための新規医薬組成物の提供。【解決手段】水溶液中に、2.0M~5.5Mの有効治療量のNa+(無機ナトリウム塩及び有機ナトリウム塩)と、250mM~3.0Mの有効治療量のCa2+(無機カルシウム塩及び有機カルシウム塩)とを含み、相乗的で、相補的な、二重波殺がん効果を生み出す医薬組成物。悪性腫瘍、がん、良性腫瘍、および非悪性過形成疾患の腫瘍内注射用製剤であって、室温で、5.0479MのNa+、250mMのCa2+、適切な量の蒸留水、10mlのUltravist370、20mgのアドレナリンと、を含む製剤。【選択図】なし