GENERATION OF PSA-ONLY PRODUCING MUTANT STRAIN

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专利权人:

发明人:

申请号：

HK15101612.9

公开号：

HK1201291B

申请日:

2015.02.13

申请国别(地区):

HK

年份:

2018

代理人:

摘要：

Provided is an isolated B. fragilis bacterial cell producing a native capsular polysaccharide A (PSA), wherein the cell is incapable of producing capsular polysaccharides PSB, PSC, PSD, PSE, PSF, PSG, and PSH because the cells biosynthetic genes for native capsular polysaccharides PSB, PSC, PSD, PSE, PSF, PSG, and PSH have been deleted from the cells genome. The isolated or wild type B. fragilis cell, or an extract obtained from said B. fragilis cell, can be used to treat individuals with inflammation.

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中国工程科技知识中心

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http://www.ckcest.cn/home/