LEE, SUNG-EUN;MAZMANIAN;MAZMANIAN, SARKIS K.; SARKIS K.;KASPER, DENNIS L.
发明人:
MAZMANIAN, SARKIS K.,KASPER, DENNIS L.,LEE, SUNG-EUN
申请号：
EP12837738
公开号：
EP2764090A4
申请日:
2012.10.03
申请国别(地区):
EP
年份:
2015
代理人:
摘要：
Provided is an isolated B. fragilis bacterial cell producing a native capsular polysaccharide A (PSA), wherein the cell is incapable of producing capsular polysaccharides PSB, PSC, PSD, PSE, PSF, PSG, and PSH because the cell's biosynthetic genes for native capsular polysaccharides PSB, PSC, PSD, PSE, PSF, PSG, and PSH have been deleted from the cell's genome. The isolated or wild type B. fragilis cell, or an extract obtained from said B. fragilis cell, can be used to treat individuals with inflammation.
