An endoluminal stent and associated methods for placing the endoluminal stent in a lumen of a trachea of a patient. The stent includes an elongate framework having a first open end, a second open end opposite the first open end, and a lumen extending from the first open end to the second open end. The elongate framework includes a first edge extending from the first open end to the second open end, a second edge extending from the first open end to the second open end, and an opening between the first edge and the second edge extending from the first open end to the second open end such that the stent has a C-shaped cross-section. The stent may be implanted in a trachea with the opening positioned along a posterior wall of the trachea adjacent the trachealis muscle.