LI BAIYONG,XIA YU,WANG ZHONGMIN,ZHANG PENG,PANG XINGHUA
申请号:
IN201747003171
公开号:
IN201747003171A
申请日:
2017.01.27
申请国别(地区):
IN
年份:
2017
代理人:
摘要:
The present invention belongs to the fields of tumor treatment and molecular immunology and provides an anti CTLA4 monoclonal antibody or an antigen binding fragment thereof a medicinal composition thereof and a use thereof. The monoclonal antibody of the present invention blocks CTLA4 from binding to B7 thereby eliminating the immunosuppressive effect of CTLA4 on the host and activating T lymphocytes.