LI BAIYONG,XIA YU,WANG ZHONGMIN,ZHANG PENG,PANG XINGHUA
申请号：
AP201709762
公开号：
AP201709762A0
申请日:
2015.07.31
申请国别(地区):
AP
年份:
2017
代理人:
摘要：
The present invention belongs to the fields of tumor therapy and molecular immunology, and provides an anti-CTLA4 monoclonal antibody or antigen binding fragment thereof, a pharmaceutical composition thereof and use thereof. The monoclonal antibody of the present invention can block the binding of CLTA4 to B7, relieve the immunosuppression on the body by CTLA4, and activate T lymphocytes.
