COMPOSITION PHARMACEUTIQUE POUR ADMINISTRATION PAR VOIE ORALE

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专利权人:

Astellas Pharma Inc.

发明人:

申请号：

EP16786506.2

公开号：

EP3290037A1

申请日:

2016.04.27

申请国别(地区):

EP

年份:

2018

代理人:

摘要：

Disclosed is a pharmaceutical composition for oral administration, comprising 1-{5-[(5-{[(2R)-2-ethylpyrrolidin-1-yl]methyl}-4-[4-methoxy-3-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl)carbamoyl]pyrazin-2-yl)pyperidine-4-carboxylic acid, which is a compound having pH-dependent solubility, or a pharmaceutically acceptable salt thereof, and a cellulose derivative. In the pharmaceutical composition for oral administration, the solubility and absorbability of the drug are improved.

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