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METHODS AND FORMULATIONS WHICH ALLOW THE MODULATION OF IMMUNE RESPONSES RELATED TO THE ADMINISTRATION OF A BIOPHARMACEUTICAL DRUG
专利权人:
发明人:
KRONTHALER ULRICH,VIERTLB–CK SCHUDY MARGOT,BARON MELANIE
申请号:
IN201617000366
公开号:
IN201617000366A
申请日:
2016.01.05
申请国别(地区):
IN
年份:
2016
代理人:
摘要:
The present invention is related to methods of preparing a pharmaceutical formulation comprising a biopharmaceutical drug which methods allows the modulation of immune responses related to the administration thereof. The formulation comprises a buffer comprising hexanedioic acid or at least one salt thereof and/or citric acid or at least one salt thereof. The present invention further relates to method of using hexanedioic acid or at least one salt thereof and/or citric acid or at least one salt thereof to modulate the immunogenicity of a pharmaceutical formulation to a pharmaceutical formulation as such and to methods of modulating or determining immune responses related to the administration of a pharmaceutical formulation (Fig. 4).
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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