LAU, Johnson Yiu-Nam,HUNG, Fan Ngai,ZHANG, Jinxia,TO, Kai Wang Kelvin,LAU, JOHNSON Yiu-Nam,YEUN, Kwok Yung
申请号:
HK18113764
公开号:
HK1254514A1
申请日:
2018.10.29
申请国别(地区):
HK
年份:
2019
代理人:
摘要:
Compositions and methods are described in which the topical application of a toll-like receptor 7 agonist or a toll-like receptor 9 agonist at or near a subdermal vaccination site provides an enhanced response to the vaccination. The enhanced response can be an elevated antibody titer relative to an untreated but vaccinated subject, and/or development of cross-species immunity to species not present in the vaccinating composition.