Fan Ngai HUNG,Jinxia ZHANG,Kai Wang Kelvin TO,Johnson Yiu-Nam LAU,Kwok Yung YUEN
申请号:
US16776403
公开号:
US20200163957A1
申请日:
2020.01.29
申请国别(地区):
US
年份:
2020
代理人:
摘要:
Compositions and methods are described in which the topical application of a toll-like receptor 7 agonist or a toll-like receptor 9 agonist at or near a subdermal vaccination site provides an enhanced response to the vaccination. The enhanced response can be an elevated antibody titer relative to an untreated but vaccinated subject, and/or development of cross-species immunity to species not present in the vaccinating composition.