VACCINE COMPOSITION COMPRISING 5-CAP MODIFIED RNA

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专利权人:

BIONTECH AG

发明人:

SAHIN UGUR,SAHIN Ugur,KUHN ANDREAS,KUHN Andreas,DARZYNKIEWICZ EDWARD,DARZYNKIEWICZ Edward,JEMIELITY JACEK,JEMIELITY Jacek,KOWALSKA JOANNA,KOWALSKA Joanna

申请号：

SI201030804

公开号：

SI2461833T1

申请日:

2010.08.03

申请国别(地区):

SI

年份:

2015

代理人:

摘要：

The present invention relates to modification of RNA with 5-cap analogs in order to improve the stability and increase the expression of said RNA, in particular in immature antigen presenting cells. The present invention provides a vaccine composition comprising said stabilized RNA, immature antigen presenting cells comprising said stabilized RNA, and methods for stimulating and/or activating immune effector cells and for inducing an immune response in an individual using said stabilized RNA.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/