An imaging agent delivery method and system thereof are provided. The method includes applying an imaging agent to a region, and alternately performing a heating process and a detecting process to the region with an ultrasound transmitting device and an ultrasound receiving device, respectively. Subsequently, an ultrasound signal acquired is processed by the ultrasound receiving device to obtain a temperature image of the region and a vaporization image of the imaging agent, such that the performance of the imaging agent can be monitored on the basis of the temperature image and the vaporization image.
