Stabilna formulacja farmaceutyczna do podawania doustnego zawierająca lewocetyryzynę lub jej farmaceutycznie dopuszczalną sól i montelukast lub jego farmaceutycznie dopuszczalną sól
KWON, TAEK KWAN,KIM, DONG HO,KIM, KYEONG SOO,KIM, YONG IL,PARK, JAE HYUN,WOO, JONG SOO
申请号：
PL13733789
公开号：
PL2800558T3
申请日:
2013.01.04
申请国别(地区):
PL
年份:
2018
代理人:
摘要：
The present invention relates to a pharmaceutical formulation for oral administration for preventing or treating allergic rhinitis or asthma, which comprises: (a) a first particle part comprising levocetirizine or a pharmaceutically acceptable salt thereof and an organic acid； and (b) a second particle part comprising montelukast or a pharmaceutically acceptable salt thereof. The pharmaceutical formulation according to the present invention comprises an organic acid as a stabilizing agent, which can effectively inhibit the production of levocetirizine and montelukast related substances, and thus, show good stability.
