The present invention provides novel compounds which activate the Kv7 potassium channels. Separate aspects of the invention are directed to pharmaceutical compositions comprising said compounds and uses of the compounds to treat disorders responsive to the activation of Kv7 potassium channels.本發明提供了活化Kv7鉀通道的新穎的化合物。本發明的單獨方面涉及包含所述化合物的醫藥組合物以及這些化合物治療對Kv7鉀通道活化有反應的障礙的用途。