11-HYDROXYL-DERIVATIVES OF BILE ACIDS AND AMINO ACID CONJUGATES THEREOF AS FARNESOID X RECEPTOR MODULATORS

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专利权人:

INTERCEPT PHARMACEUTICALS; INC.

发明人:

PELLICCIARI, ROBERTO

申请号：

PH12015502576

公开号：

PH12015502576A1

申请日:

2015.11.13

申请国别(地区):

PH

年份:

2016

代理人:

摘要：

The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt, solvate, or amino acid conjugate thereof, wherein R1 is a hydroxy group and R2, R3, R4, R5, and R6 are as described herein. The present invention relates generally to selective FXR agonists and to methods of making and using them.

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中国工程科技知识中心

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http://www.ckcest.cn/home/