11-HYDROXYL-DERIVATIVES OF BILE ACIDS AND AMINO ACID CONJUGATES THEREOF AS FARNESOID X RECEPTOR MODULATORS

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专利权人:

INTERCEPT PHARMACEUTICALS; INC.

发明人:

PELLICCIARI, ROBERTO

申请号：

SG11201509352X

公开号：

SG11201509352XA

申请日:

2014.05.14

申请国别(地区):

SG

年份:

2015

代理人:

摘要：

The present invention provides a compound of formula (I): or a pharmaceutically acceptable salt, solvate, or amino acid conjugate thereof, wherein R 1 is a hydroxy group and R 2 , R 3 , R 4 , R 5 , and R 6 are as described herein. The present invention relates generally to selective FXR agonists and to methods of making and using them.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/