DÉRIVÉS DE 3-PHÉNYL-5-UREIDOISOTHIAZOLE-4-CABOXIMIDE ET DE 3-AMINO-5-PHÉNYLISOTHIAZOLE EN TANT QU'INHIBITEURS DE KINASE

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专利权人:

ALLERGAN; INC.

发明人:

申请号：

EP17156014.7

公开号：

EP3184525A1

申请日:

2012.12.27

申请国别(地区):

EP

年份:

2017

代理人:

摘要：

This invention is directed to a compound of Formula Ior a pharmaceutically acceptable salt thereof, wherein R, R1, R2, R3, n, X1, X2, L1, and L2 are as defined herein. The compounds of Formula I are useful as receptor tyrosine kinase (RTK) inhibitors and can be used to treat such diseases as cancer, blood vessel proliferative disorders, fibrotic disorders, mesangial cell proliferative disorders and metabolic diseases.

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中国工程科技知识中心

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http://www.ckcest.cn/home/