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Succinic acid salt of the 1- [2- (2-chloro-4 - {[(R) -2-hydroxy-2- (8-hydroxy-2-oxo-1,2-dihydroquinolin-5-yl) ethylaminomethyl ester ]} - 5-Methoxyphenylcarbamoyl) ethyl] biphenyl-2-ylcarbamic acid piperidin-4-yl and its use for the treatment of pulmonary disorders
专利权人:
GLAXO GROUP LIMITED
发明人:
CHUDASAMA, Reshma,KENNEDY, Andrew,KINDON, Leanda,MALLET, Franck
申请号:
ES07704449
公开号:
ES2640226T3
申请日:
2007.02.08
申请国别(地区):
ES
年份:
2017
代理人:
摘要:
An ester succinic acid salt 1- [2- (2-chloro-4 - {[(R) -2-hydroxy-2- (8-hydroxy-2-oxo-1,2-dihydroquinolin-5- yl)) ethylamino] methyl} -5-methoxyphenylcarbamoyl) ethyl] piperidin-4-yl of biphenyl-2-ylcarbamic acid, which is the crystalline solid form Form 1 characterized by an X-ray powder diffraction pattern that has diffraction peaks at 2θ values of 5.0, 5.7, 7.1, 10.0, 12.6, 13.8, 14.4, 15.5, 16.1, 16.4, 16.9, 17 , 8, 18.5, 20.2, 20.5, 21.4, 25.3, 25.8 and 26.3.Una sal de ácido succínico de éster 1-[2-(2-cloro-4-{[(R)-2-hidroxi-2-(8-hidroxi-2-oxo-1,2-dihidroquinolin-5- il)etilamino]metil}-5-metoxifenilcarbamoil)etil]piperidin-4-ílico del ácido bifenil-2-ilcarbámico, que es la forma en estado sólido cristalino Forma 1 caracterizada por un patrón de difracción de rayos X de polvo que tiene picos de difracción a valores de 2θ de 5,0, 5,7, 7,1, 10,0, 12,6, 13,8, 14,4, 15,5, 16,1, 16,4, 16,9, 17,8, 18,5, 20,2, 20,5, 21,4, 25,3, 25,8 y 26,3.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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