crystalline free base forms of a biphenyl compound

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专利权人:

INC.;Theravance

发明人:

Grahame Woollam

申请号：

BR112012000890

公开号：

BR112012000890A2

申请日:

2010.07.14

申请国别(地区):

BR

年份:

2017

代理人:

摘要：

The invention provides a crystalline freebase form of biphenyl-2-ylcarbamic acid 1-(2-{[4-(4-carbamoylpiperidin-1-ylmethyl)benzoyl]methylamino}ethyl)piperidin-4-yl ester. The invention also provides pharmaceutical compositions comprising the crystalline freebase or prepared using the crystalline freebase； processes and intermediates for preparing the crystalline freebase； and describes methods of using the crystalline freebase to treat a pulmonary disorder.

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中国工程科技知识中心

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