To maintain high estimation accuracy of the activity in the autonomic nerves.An information processing apparatus according to the present technology includes: a processing section that executes a process including a correction process of specifying noise included in perspiration data acquired by a perspiration sensor on a basis of sensor data acquired by a different type of sensor than the perspiration sensor, and removing the noise from the perspiration data. According to such a technology, noise estimated according to other sensor data can be removed from the perspiration data, making it possible to maintain high accuracy in a later process of estimating activity in the autonomic nerves.