Alan r brooks,John E Murphy,MARIAN SETO,XIAOQIAO JIANG,DAVID KIEWLICH,CHANDRA PATEL
申请号：
IN7334/DELNP/2010
公开号：
IN2010DN07334A
申请日:
2010.10.18
申请国别(地区):
IN
年份:
2012
代理人:
摘要：
The invention relates to modified Factor IX polypeptides such as Factor IX polypeptides with one or more introduced cysteine sites. The modified Factor IX polypeptides may be conjugated to a biocompatible polymer. The invention also relates to methods of making modified Factor IX polypeptides, and methods of using modified Factor IX polypeptides, for example, to treat patients afflicted with hemophilia B.
