NORMINGTON, KARL D.,SINCLAIR, DAVID A.,LIVINGSTON, DAVID,MCKEARIN, JAMES M.,SZCZEPANKIEWICZ, BRUCE,KREMSKY, JONATHAN N.
申请号:
CA2994553
公开号:
CA2994553A1
申请日:
2016.08.05
申请国别(地区):
CA
年份:
2017
代理人:
摘要:
The invention relates to compositions of nicotinamide mononucleotide derivatives and their methods of use. The invention also relates to methods of preparing nicotinamide mononucleotide derivatives. The invention relates to pharmaceutical compositions and nutritional supplements containing a nicotinamide mononucleotide derivative. The invention relates to methods of using nicotinamide mononucleotide derivatives that promote the increase of intracellular levels of nicotinamide adenine dinucleotide (NAD+) in cells and tissues for treating diseases and improving cell and tissue survival.