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PROCÉDÉ DE PRÉPARATION DE GRANULÉS SÉCHÉS AU MOINS EN PARTIE
专利权人:
Novartis AG
发明人:
申请号:
EP18773638.4
公开号:
EP3675829A1
申请日:
2018.08.30
申请国别(地区):
EP
年份:
2020
代理人:
摘要:
In a method for preparing at least partially dried granules (56) an API (12), a base powder (14) and a granulation liquid (15) are fed to a granulator (16). The API (12), the base powder (14) and the granulation liquid (15) are mixed within the granulator (16) in order to produce an API/base powder/granulation liquid mixture. The API/base powder/granulation liquid mixture within the granulator (16) is heated to a heating temperature (TH) that exceeds an evaporation temperature (TE) of the granulation liquid (15) contained in the API/base powder/granulation liquid mixture so as to allow at least a part of the granulation liquid (15) contained in the API/base powder/granulation liquid mixture to evaporate in order to obtain at least partially dried granules (56) containing at least the API (12) and the base powder (14). The at least partially dried granules (56) are discharged from the granulator (16).
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