A system for locating a target tissue site is described. The system includes a locating guide that frames an area of interest upon placement over skin of a patient, an electrode patch defining an aperture and including two or more electrodes for placement within the area of interest, and a medical imaging device that indicates a location of a target tissue site within the patient based on electrical signals generated by one or more of the electrodes. A clinician may guide an introducer needle into the aperture for implanting a medical lead proximate to the target tissue site.
