1,6-diazabicyclo [3,2,1] octane-7-one derivatives and their use in the treatment of bacterial infections农业专利-农业学术服务平台

发明人:: PATIL, Vijaykumar,TADIPARTHI, Ravikumar,DOND, Bharat,KALE, Amol,VELUPILLAI, Loganathan,DEKHANE, Deepak,BIRAJDAR, Satish,SHAIKH, Mohammad,MAURYA, Sushilkumar,PATEL, Piyush,DIXIT, Prasad,PAWAR, Mangesh

摘要：: Compound of Formula (I) ** Formula ** or a stereoisomer or a pharmaceutically acceptable salt thereof； where: R1 is SO3M； M is hydrogen or a cation； R2 is: (a) hydrogen, (CH2) n-R3, or COOR3, n is 0, 1 or 2； R3 is: (a) hydrogen, (b) C1-C6 alkyl substituted with heterocyclyl, said heterocyclyl being substituted with one or more substituents chosen from the group consisting of C1-C6 alkyl, halogen, CN, COOH, CONH2, OH, NH2 and NHCOCH3.Compuesto de Fórmula (I)**Fórmula** o un estereoisómero o una sal farmacéuticamente aceptable del mismo； donde: R1 es SO3M； M es hidrógeno o un catión； R2 es: (a) hidrógeno, (CH2)n-R3, o COOR3, n es 0, 1 o 2； R3 es: (a) hidrógeno, (b) alquilo C1-C6 sustituido con heterociclilo, estando dicho heterociclilo sustituido con uno o más sustituyentes elegidos del grupo que consiste en alquilo C1-C6, halógeno, CN, COOH, CONH2, OH, NH2 y NHCOCH3.