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Formulation Obtained from a Powder Mixture Comprising an Inorganic Pigment
专利权人:
Abbvie Deutschland GmbH & CO. KG
发明人:
Katja Fastnacht,Matthias Degenhardt,Gunther Berndl,Jörg Rosenberg,Jörg Breitenbach
申请号:
US15906263
公开号:
US20180185287A1
申请日:
2018.02.27
申请国别(地区):
US
年份:
2018
代理人:
摘要:
A solid dosage form having a matrix with at least one active compound dispersed homogeneously in the matrix, which is obtainable by melting a powder mixture, wherein the powder mixture comprises at least one thermoplastic binder and a combination of highly disperse silica and at least one inorganic pigment, is described. The co-use of the highly disperse silica and the inorganic pigments leads to better flow properties of the powder mixture, has the effect of a faster release of the active compound from the dosage forms obtained, and imparts a visually pleasing appearance to the dosage forms. A process for the preparation of the dosage form is also described.
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