PARREN, PAUL,BEURSKENS, FRANK,DE JONG, ROB N.,VERPLOEGEN, SANDRA,LABRIJN, ARAN FRANK,SCHUURMAN, JANINE
申请号：
CA2896955
公开号：
CA2896955A1
申请日:
2013.01.10
申请国别(地区):
CA
年份:
2014
代理人:
摘要：
Described herein are polypeptides and related antibodies comprising a variant Fc domain. The variant Fc domain provide for stabilized Fc: Fc interactions when the polypeptide(s), antibody or antibodies are bound to its target, antigen or antigens on the surface of a cell, thus providing for improved complement-dependent cytotoxicity (CDC).
