The present invention relates to a compound of general formula (III) or a salt thereof, a solvate or a prodrug thereof, as well as to medical use, which provides for them, where A is selected from the group consisting of N and C-R； A selected from the group consisting of N and C — R； A selected from the group consisting of N and C — R； A, and A, and An are independently selected from the group consisting of N and C — R； R is selected from the group consisting of hydrogen, (C-C) alkyl, halogen, (C-C) alkoxy and (C-C) haloalkyl； R is selected from the group consisting of hydrogen, halogen, and (C-C) alkyl； R is selected from the group consisting of hydrogen, (C-C) alkyl, NRR, (C-C) alkyl-NRR and cyano； wherein R and R are independently selected from the group consisting of hydrogen, (CC) cycloalkyl, (CC) heterocycloalkyl, (CC) alkyl, or R and R together with the nitrogen atom to which they are attached, form a 5-7 membered heterocyclic ring, optionally containing addition to the above nitrogen atom is an additional heteroatomic group selected from the group consisting of O and NR, where R is selected from the group consisting of hydrogen, methyl, acetyl and formyl； Y is selected from the group consisting of O and S； R is selected from the group consisting of hydrogen and (C-C) alkyl； R is selected from the group consisting of (C-C) alkyl, (C-C) cycloalkyl and (C-C) heterocycloalkyl； R is selected from the group consisting of hydrogen, (C-C) alkyl, (C-C) alkoxy, and to methods for the preparation of these compounds.Настоящее изобретение относится к соединению общей формулы (III) или его соли, сольвату или пролекарству, а также к применению в медицине, которое их предусматривает,где A1 выбран из группы, состоящей из N и C-R8； A2 выбран из группы, состоящей из N и C-R3； A3 выбран из группы, состоящей из N и C-R9； A4, и A5, и A6 независимо выбраны из группы, состоящей из N и C-R1； R1 выбран из группы, состоящей из водорода, (C1-C3)алкила, галогена, (C1-C3)алкокси и (C1-C3
