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Immunosuppressive cell-capturing material and immunosuppressive cell-capturing column
专利权人:
Kazumasa Ogasawara
发明人:
Kazumasa Ogasawara,Kazuo Teramoto,Yuji Ueda,Yasushi Itoh,Hirohito Ishigaki
申请号:
US14008538
公开号:
US09127250B2
申请日:
2012.03.27
申请国别(地区):
US
年份:
2015
代理人:
摘要:
This invention discloses an immunosuppressive cell-capturing material comprising a molded body that includes: a readily hydrolyzable condensation polymer having an amino group a poorly hydrolyzable polymer coating the readily hydrolyzable condensation polymer and a ligand-conjugated poorly hydrolyzable polymer coating the poorly hydrolyzable polymer, wherein the ligand is at least one selected from the group consisting of a NH2 group, a secondary amino group, a tertiary amino group, a polyamine residue, a basic cyclic polypeptide residue, an aminoglycosidic compound residue, chloroquine, primaquine, mefloquine, imiquimod, and nystatin, and wherein the content of the amino group in the molded body is 150 μmol/g or less. The invention also discloses an immunosuppressive cell-capturing column filled with the capturing material.
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