WENG, BOR CHUN,翁博群,翁博群,CHEN, LI GEENG,陈立耿,陳立耿,CHEN, CHUN HSIEN,陈俊宪,陳俊憲,WUNG, BEING SUN,翁炳孙,翁炳孫
申请号：
TW105112685
公开号：
TW201737934A
申请日:
2016.04.22
申请国别(地区):
TW
年份:
2017
代理人:
摘要：
A pharmaceutical composition and an application in preventing or decreasing diabetes and its complications by administering the pharmaceutical composition, which is characterized by the pharmaceutical composition including a plant-based mixture that comprises soy isoflavones and peanut stilbenes abundantly in soybeans and peanuts, respectively. The pharmaceutical composition tested in vitro has decreased the amount of reactive oxygen species (ROS) of the renal epithelial cells in the high-glucose medium. In in vivo study, the pharmaceutical composition elevates the serum concentration of insulin, decreases the concentration of blood sugar and blood lipid, and decreases the activity of alanine aminotransferase in attribution to decrease inflammation and ameliorate diabetes and its complications.本發明有關於一種醫藥組成物及其用於預防或減緩糖尿病及其併發症的用途,其特徵在此醫藥組成物包含植物來源混合物,其包含大豆中所富含的大豆異黃酮與花生中所富含的對苯乙烯衍生物。此醫藥組成物於活體外的高葡萄糖環境中可降低腎上皮細胞之自由基含量,以及於活體內提昇胰島素濃度、降低血糖與血脂含量、降低肝臟丙胺酸轉胺酶活性以及降低發炎反應等,藉此預防或減緩糖尿病及其併發症。301/303/305/307‧‧‧曲線
