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Coated oncolytic adenoviruses for cancer vaccines
专利权人:
Helsingin Yliopisto
发明人:
Cerullo, Vincenzo,Vaha-Koskela, Markus,Hirvinen, Mari,Capasso, Cristian
申请号:
AU2015263286
公开号:
AU2015263286A1
申请日:
2015.05.18
申请国别(地区):
AU
年份:
2016
代理人:
摘要:
The present invention relates to adenoviral vectors, wherein the viral capsid has been coated with polypeptides, which are capable of stimulating a peptide-specific immune response in a subject and uses thereof. Furthermore, the present invention relates to methods of treating diseases, e.g. cancer, by adenoviral vectors which have been coated by polypeptides causing peptide-specific immune response. Also the present invention relates to a method of coating adenoviral vectors by specific peptides as well as to a method of identifying those peptides suitable for coating the capsid of an adenoviral vector.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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