Marion Wiesmann;Keith B. Pfister;James Sutton;Allan S. Wagman;Simon C. Ng;Martin Sendzik
发明人:
Simon C. Ng,Keith B. Pfister,Martin Sendzik,James Sutton,Allan S. Wagman,Marion Wiesmann
申请号：
US12451326
公开号：
US08293769B2
申请日:
2008.05.20
申请国别(地区):
US
年份:
2012
代理人:
摘要：
Benzoxazole and benzothiazole compounds and their oxides, esters, prodrugs, solvates, and pharmaceutically acceptable salts thereof are disclosed. Compositions of the compounds, either alone or in combination with at least one additional therapeutic agent, with a pharmaceutically acceptable carrier, and uses of the compounds, either alone or in combination with at least one additional therapeutic agent are also disclosed. The embodiments are useful for inhibiting cellular proliferation, inhibiting the growth and/or metathesis of tumors, treating or preventing cancer, treating or preventing degenerating bone diseases such as rheumatoid arthritis, and/or inhibiting molecules such as CSF 1R.
