SUTTON James C.,WIESMANN Marion,WANG Weibo,LINDVALL Mika K.,LAN Jiong,RAMURTHY Savithri,SHARMA Anu,MIEULI Elizabeth J.,KLIVANSKY Liana M.,LENAHAN William P.,KAUFMAN Susan,YANG Hong,NG Simon C.,PFISTER,MI
申请号:
SI200731995
公开号:
SI2010528T1
申请日:
2007.04.18
申请国别(地区):
SI
年份:
2018
代理人:
摘要:
Benzoxazole and benzothiazole compounds and the stereoisomers, tautomers, solvates, oxides, esters, and prodrugs thereof and pharmaceutically acceptable salts thereof are disclosed. Compositions of the compounds, either alone or in combination with at least one additional therapeutic agent, with a pharmaceutically acceptable carrier, and uses of the compounds, either alone or in combination with at least one additional therapeutic agent are also disclosed. The embodiments are useful for inhibiting cellular proliferation, inhibiting the growth and/or metathesis of tumors, treating or preventing cancer, treating or preventing degenerating bone diseases such as rheumatoid arthritis, and/or inhibiting molecules such as CSF-1R.