DANIEL E. DOBRY,DAVID K. LYON,DAVID T. VODAK,DWAYNE T. FRIESEN,WARREN K. MILLER,WILLIAM B. CALDWELL
申请号:
BR112012031667
公开号:
BR112012031667A2
申请日:
2011.06.13
申请国别(地区):
BR
年份:
2016
代理人:
摘要:
Disclosed are polymers of hydroxypropyl methyl cellulose acetate succinate (HPMCAS) with unique degrees of substitution of hydroxypropoxy, methoxy, acetyl, and succinoyl groups. When used in making compositions comprising a low-solubility active agent and such polymers, the polymers provide increased aqueous concentrations and/or improved physical stability of the active agent.