An antibody-conjugated double emulsion core-shell nano structure is provided. A reactive functional group is introduced on the surface of a double emulsion core-shell nano structure, which is made from an oil shell enclosing a water core, to conjugate with an antibody.本發明提供一種架接抗體之雙乳化核殼奈米結構。在油相殼包覆水相核而成之雙乳化核殼奈米結構的表面引進架橋基,以與抗體相接,形成架接抗體之雙乳化核殼奈米結構。100‧‧‧雙乳化核殼奈米結構110‧‧‧油相殼115‧‧‧高分子120‧‧‧疏水性磁奈米粒子125‧‧‧水相核130‧‧‧架橋基135‧‧‧抗體140‧‧‧疏水性藥物145‧‧‧親水性藥物