The present invention relates to a multi-layer material comprising a metal or metal alloy substrate, the metal or alloy substrate being coated with an intermediate layer comprising at least one ceramic or crystalline, or partially crystalline, structure, including a metal or a metal alloy, said intermediate layer being coated with a layer of calcium phosphate having a cellular nanometric structure, and uses thereof.The present invention relates to the method for preparing such a material by autocatalytic deposition of a layer of calcium phosphate comprising a cellular nanometric surface structure.