The Brigham and Women's Hospital, Inc.;Children's Medical Center Corporation
发明人:
申请号：
EP16177814.7
公开号：
EP3130923A1
申请日:
2009.11.13
申请国别(地区):
EP
年份:
2017
代理人:
摘要：
Genes that are deregulated in cancer stem cells (e.g., melanoma stem cells) are disclosed. Methods which involve modulating (e.g., inducing, inhibiting, etc.) the activity of the cancer stem cell associated genes are used to treat individuals having melanoma. Cell surface genes that are upregulated in melanoma stem cells are targeted for the selective isolation, detection, and killing of cancer stem cells in melanoma.
