CHUA, PETER C.,PIERRE, FABRICE,WHITTEN, JEFFREY P.
申请号：
CA2974246
公开号：
CA2974246C
申请日:
2007.08.31
申请国别(地区):
CA
年份:
2020
代理人:
摘要：
This specification provides pharmaceutical compositions comprising therapeuticagentsof formula TA4-1:(see formula)and compounds that inhibit poly(ADP-ribose)polymerase activity (PARP) and/orcasein kinase2 activity (CK2), having the structure of formula XIIa or formula XIII:(see formula)and methods of using such pharmaceutical compositions having certainbiological activities thatinclude, but are not limited to, inhibiting cell proliferation, inducing cellapoptosis, modulatingprotein kinase activity, modulating polymerase activity, and treating cellproliferativeconditions.
