The present invention relates to compositions and methods for treating,preventing and improving the condition and aesthetic appearance of skin,particularly, treating, preventing, ameliorating, reducing and/or eliminatingfine lines and/or wrinkles of skin, where the compositions include naturalplant constituents which increase expression levels genes associated with thedermatological signs of aging. The compositions of the invention are topicallyapplied to the skin, or are delivered by directed means to a site in needthereof, once daily in an amount effective in improving the condition andaesthetic appearance of skin.