The present invention relates to formula (I) therapeutic agents or its pharmaceutical salt as atypical antipsychotic agents. They can use what treatment nerve related with dopamine D 2 and serotonin 5-HT2A neurotransmission dysfunctions and phrenoblabia, wherein R1 is unsubstituted or by a fluorine-substituted C1-6 alkyl of 1-6, and wherein the hydroxyl on R1 and ring is connected on same carbon atom.本發明涉及作爲非典型抗精神病藥的式(I)治療劑或其可藥用的鹽。它們可用於治療與多巴胺D2和5-羥色胺5-HT2A神經傳遞功能不良有關的神經和精神障礙，其中，R1是未取代的或被1-6個氟取代的C1-6烷基，其中R1和環上的羥基連接在同一碳原子上。
