IMPROVEMENT OF THE BIOAVAILABILITY OF ACTIVE SUBSTANCES HAVING AN AMIDINE FUNCTION IN MEDICAMENTS

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专利权人:

DRITTE PATENTPORTFOLIO BETEILIGUNGSGESELLSCHAFT MBH & CO. KG

发明人:

CLEMENT BERND,CLEMENT Bernd,REEH CHRISTIANE,REEH Christiane

申请号：

SI200731707

公开号：

SI2046732T1

申请日:

2007.07.10

申请国别(地区):

SI

年份:

2016

代理人:

摘要：

The invention relates to the use of N,N-dihydroxyamidine (I), N,N-dihydroxyamidine ether (II), N,N-dihydroxyamidine diether (III), N,N-dihydroxyamidine ester (IV), N,N-dihydroxyamidine diester (V) or 4-hydroxy-1,2,4-oxadiazoline (VI) of the formulae cited above, wherein R represents hydrogen, an alkyl and/or aryl radical, as a substitute for an amidine function of a medicament for improving the bioavailability of the medicament.

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