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Silicon containing calcium acrylate compounds for outer atmosphere management
专利权人:
NOVEN PHARMACEUTICALS; INC.
发明人:
STEVEN DINH,PUCHUN LIU,JILIN ZHANG,JUN LIAO
申请号:
ARP150102416
公开号:
AR101358A1
申请日:
2015.07.28
申请国别(地区):
AR
年份:
2016
代理人:
摘要:
Claim 1: a composition for the transdermal Administration of a drug containing amino groups in the form of a flexible system of Limited Dimensions (Patch) for topical Application, characterized in that it comprises a Polymer Matrix comprising a Drug and a Pol u00edmero containing Silicone Acrylic.Claim 7: the composition of claim 1, wherein the Acrylic Polymer containing Silicon is made of one or more non reactive Acrylic monomers containing Silicones are selected from the group consisting of: 3 - (trimethylsiloxy) acriloxipropil Tri Sila No, metacriloxipropil TRI 3 - (trimethylsiloxy) silane, siloxane and finished in mono VinylAcrylic monomers and one or more non reactive monomers, where no Reagents do not react with the amino groups of the drug containing amino groups. Claim 9: the composition of claim 1, wherein the drug is a drug containing Amine groups are selected from the group consisting of: Amphetamine, methylphenidate, rivastigmine, paroxetine and clonidine.Claim 12: a method for transdermal Administration of a drug containing amino groups, characterized in that it comprises a composition is topically applied as claimed in claim 1, to the skin or a mucous membrane of a Subject that needs IT.Claim 13: a method for preparing a composition for the transdermal Administration of a drug containing amino groups in the form of a flexible system of Limited Dimensions for topical Application, characterised in that it comprises forming a mixture of polymeric Matrix m Ezclando a drug containing amino groups and an acrylic Polymer containing Silicone in a SolventApply the mixture of Polymer Matrix and a support Layer, remove the remaining solvent. Claim 14: a method for preparing a Silicone containing Acrylic Polymer, characterized in that it comprises copolimerizar Acrylic monomers with acrylic monomers containing silicon.Claim 16: Method of claim 14, wherein the Acrylic Polymer containing Silicones comprises 1 to 99% by weight of Acrylic monomers and 99 to 1% by wei
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