Composition comprising inhibitor against PAPSS2 gene or protein encoded by gene for inducing senescence in tumor cells and method for inducing senescence in tumor cells using the same
Jae-Seon Lee,Seung Hee Jung,Bong Cho Kim,Hyung Chul Lee,Na-Kyung Han,Mi-Na Hong
申请号:
US14421619
公开号:
US09550995B2
申请日:
2013.05.20
申请国别(地区):
US
年份:
2017
代理人:
摘要:
Provided is a composition for inducing tumor cell senescence and a method for inducing tumor cell senescence using the same. The composition can inhibit a PAPSS2 gene in a tumor cell to thereby induce senescence of the tumor cell, and if the composition is used concurrently with irradiation of the tumor cell, the composition can improve the sensitivity of the tumor cell to radiation.