A sterile drug dispensing system, comprising: an air source output device, a handle and a drug dissolving device； the drug dissolving device is detachably mounted on the handle, the handle being connected to the air source output device by means of a power line and an air pipe, being for use in filtering gas and controlling the gas source output device； the gas source output device is used for outputting and extracting gas. A sterile drug dispensing method, which corresponds to the operating steps of the sterile drug dispensing system.
