DAVID R. LANCIA,DAVID S. MILLAN,HONGBIN LI,JAMES LOCH,KENNETH W. BAIR,MARK J. TEBBE,MATTHEW W. MARTIN,SHAWN E. R. SCHILLER,WEI LU
申请号：
BR112015023279
公开号：
BR112015023279A2
申请日:
2014.03.11
申请国别(地区):
BR
年份:
2017
代理人:
摘要：
The present invention relates to a list of specific 2-hydroxy-1-{4-[(4-phenylphenyl)carbonyl]piperazin-1-yl}ethan-1-one derivatives and related compounds as fatty acid synthase (FAS or FASN) inhibitors for treating cancer and pharmacutical compositions thereof .An illustrative compound of the invention is shown below:
