CHEN, LI,FENG, LICHUN,HAWLEY, RONALD CHARLES,YANG, MINMIN,DILLON, MICHAEL PATRICK
申请号:
HK13111857.4
公开号:
HK1184453B
申请日:
2013.10.22
申请国别(地区):
HK
年份:
2016
代理人:
摘要:
Compounds of the formula I: or a pharmaceutically acceptable salt thereof, wherein, R 1 is optionally substituted tetrazolyl, R 2 is optionally substituted phenyl, optionally substituted pyridinyl or optionally substituted thienyl, and R 3 , R 4 , R 5 and R 6 are as defined herein. Also provided are methods of using the compounds for treating diseases mediated by a P2X 3 and/or a P2X 2/3 receptor antagonist and methods of making the compounds.