ARYLAMIDES À SUBSTITUTION THIADIAZOLE

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专利权人:

F. HOFFMANN-LA ROCHE AG

发明人:

申请号：

EP09768366.8

公开号：

EP2379518B1

申请日:

2009.12.07

申请国别(地区):

EP

年份:

2014

代理人:

摘要：

Compounds of the formula I: or a pharmaceutically acceptable salt thereof, wherein, R1 is optionally substituted thiadiazolyl, and R2, R3, R4, R5, R6, R7 and R8 are as defined herein. Also disclosed are methods of using the compounds for treating diseases associated with P2X3 and/or a P2X2/3 receptor antagonists and methods of making the compounds.

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