INDIANA UNIVERSITY RESEARCH & TECHNOLOGY CORPORATION
发明人:
PILI, ROBERTO
申请号:
CA3013047
公开号:
CA3013047A1
申请日:
2017.01.27
申请国别(地区):
CA
年份:
2017
代理人:
摘要:
Compositions including combinations of class I histone deacetylase (HDAC) inhibitors and programmed cell death protein 1 (PD-1) inhibitors for enhancing antitumor activity are disclosed. Further disclosed are methods of administering these compositions as immunotherapies for suppressing regulatory T cells in renal cell carcinoma.