Michael Klein,Joseph Fisher,James Duffin,Marat Slessarev,Cathie Kessler,Shoji Ito
申请号:
US15585999
公开号:
US20170361042A1
申请日:
2017.05.03
申请国别(地区):
US
年份:
2017
代理人:
摘要:
A processor obtains input of a logistically attainable end tidal partial pressure of gas X (PetX[i]T) for one or more respective breaths [i] and input of a prospective computation of an amount of gas X required to be inspired by the subject in an inspired gas to target the PetX[i]T for a respective breath [i] using inputs required to utilize a mass balance relationship, wherein one or more values required to control the amount of gas X in a volume of gas delivered to the subject is output from an expression of the mass balance relationship. The mass balance relationship is expressed in a form which takes into account (prospectively), for a respective breath [i], the amount of gas X in the capillaries surrounding the alveoli and the amount of gas X in the alveoli, optionally based on a model of the lung which accounts for those sub-volumes of gas in the lung which substantially affect the alveolar gas X concentration affecting mass transfer.