The invention refers to an antimicrobial, exfoliating and seboregulating hydrosoluble composition comprising a combination of diallyl disulphide modified oxide (DDMO) and alpha hydroxyethanoic acid (glycolic acid), which acts removing bacteria affecting the skin including those caused by acne, said composition also provides deep cleansing, exfoliating action, reduces epidermal cohesion facilitating cellular change, preventing the occurrence of several forms of acne in the skin and additionally producing seboregulating effects by avoiding blockage of sebaceous glands.本發明涉及一種具抗菌、調節皮脂分泌及去角質功效之水溶性組成物,其組成含有二烯丙基二硫轉化修飾氧化物(diallyl disulphide modified oxide,DDMO)和α-羥基乙酸(alpha hydroxyethanoic acid,glycolic acid/乙醇酸),其作用包括去除由粉刺引起會影響皮膚之細菌,本組成物且能提供深層潔淨、去角質並減少表皮的凝聚力,防止數種形態之粉刺在皮膚發生,另外影響形成調節皮脂分泌,避免皮脂腺之堵塞。